The Microsoft SharePoint Team Blog (http://blogs.msdn.com/b/sharepoint/archive/2010/09/21/security-advisory-2416728-vulnerability-in-asp-net-and-sharepoint.aspx) lists WORKAROUND steps that should be taken for SharePoint Web Front Ends (WFE’s) to mitigate the vulnerability related to ASP.NET.
Follow the link above to find the steps for your version of SharePoint and implement this in your environment. It only takes a few minutes!